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Competitive Advantages

Stable, highly functional mRNA, yields, one-step process …

The C3P3® mRNA Production System has three decisive competitive advantages:

  • Yields: increased mRNA yields, enhancing protein expression
  • Capping and polyadenylation: fully mature mRNA with very high rate of native capping and 100% proper cap orientation, and poly(A)tail, enhancing protein expression as well
  • Easy-to-Use and Quick: One-step process instead of 3 or 4 to produce completely capped, poly(A)-tailed mRNA

 

There are other major advantages

  • Stability and immunogenicity: potential to incorporate modified nucleosides such as 5’-Methylcytidine-5’-Triphosphate and Pseudouridine-5’-Triphosphate to reduce innate immune response in transfected cells, to enhance translation and to increase nuclease resistance
  • Compatible with any mRNA purification process, including FPLC or HPC
  • Poly(A)-tails of equal or customized length
  • Additional specifications can be incorporated into template design
  • Non-viral technology

 

C3P3® Technology advantages for mRNA synthesis

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